Professor Sarathy's research interest is in developing sustainable energy technologies with decreased net environmental impact. A major thrust of research is simulating the combustion chemistry of transportation fuels. He develops fundamental chemical kinetic models that can be used to simulate fuel combustion and pollutant formation in energy systems. Engine designers then use these chemical kinetic models to achieve various performance targets using computational simulations. In addition, these models can be used to determine how the chemical structure of a fuel affects pollutant formation. 

The goal of Professor Sarathy's research is study conventional and alternative fuels (e.g., biofuels, synthetic fuels, etc.), so the environmental impact of combustion systems can be reduced. He also applies chemical kinetics expertise to study a wide range of chemical engineering systems including biomass energy, catalysis, and drinking water treatment.